DAPM Chemical Properties

Boiling point:

601.0±55.0 °C(Predicted)

Density 

1.272±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: 2mg/mL

pka

12.82±0.46(Predicted)

form 

solid

color 

white

Sequence

N-[N-3,5-Difluorophenacetyl]-L-alanyl-S-phenylglycine methyl ester

InChI

1S/C20H20F2N2O4/c1-12(23-17(25)10-13-8-15(21)11-16(22)9-13)19(26)24-18(20(27)28-2)14-6-4-3-5-7-14/h3-9,11-12,18H,10H2,1-2H3,(H,23,25)(H,24,26)/t12-,18-/m0/s1

InChIKey

XAPDRNSTUYCSQC-SGTLLEGYSA-N

Safety Information

WGK Germany 

WGK 1

Storage Class

11 - Combustible Solids

DAPM Usage And Synthesis

Uses

gamma-Secretase Inhibitor XVI is a γ-secretase inhibitor that selectively blocks Aβ dimer and trimer formation.

Biological Activity

Cell permeable: yes', 'Primary Target
γ-secretase Aβ40 in 7PA2 cells', 'Product does not compete with ATP.', 'Reversible: no

DAPM(208255-51-0)Related Product Information

• DAPT
• BETA-SECRETASE INHIBITOR IV
• γ-Secretase Inhibitor XXI
• DIBENZAZEPINE
• GAMMA-SECRETASE INHIBITOR
• DAPM
• AC-PHG-OME