1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Basic information
- Product Name:
- 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
- Synonyms:
-
- 1-(5-isoquinolinesulfonyl)-2-methylpiperazine
- 1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin
- 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
- 1-(5-isoquinolinylsulfonyl)-2-*methylpiperazine F
- 1-(5-ISOQUINOLINYLSULFONYL)-2-*METHYLPIP ERAZINE FRE
- H-72HCl
- 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide
- (Isoquinoline-5-yl)(2-methylpiperazine-1-yl) sulfone
- CAS:
- 84477-87-2
- MF:
- C14H17N3O2S
- MW:
- 291.37
- Mol File:
- 84477-87-2.mol
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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Chemical Properties
- Boiling point:
- 495.3±55.0 °C(Predicted)
- Density
- 1.277±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- ethanol: 20 mg/mL
- pka
- 7.69±0.40(Predicted)
- form
- Solid
- color
- White to light yellow
- BRN
- 5482740
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Safety Information
- WGK Germany
- 3
- RTECS
- TL9305000
- F
- 10
- Toxicity
- LD50 intravenous in mouse: 94mg/kg
MSDS
- Language:English Provider:SigmaAldrich
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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Usage And Synthesis
Definition
ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
Biological Activity
Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINESupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
Shanghaizehan biopharma technology co., Ltd.
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- 021-61350663 13052117465
- sales@zehanbiopharma.com
EMMX Biotechnology LLC
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- 888-539-0666
- info@emmx.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Shanghai Chaolan Chemical Technology Center
- Tel
- 021-QQ：65489617 15618227136
- Sales@ATKchemical.com
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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE(84477-87-2)Related Product Information
- 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE
- 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE
- 1-METHANESULFONYL-PIPERAZINE
- 1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE
- 1-BENZENESULFONYL-PIPERAZINE
- 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
- (S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride
- 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE
- (R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride