Tetramethoxymethane Chemical Properties

Melting point:

-5 °C (lit.)

Boiling point:

114 °C (lit.)

Density 

1.023 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.385(lit.)

Flash point:

44 °F

storage temp. 

Refrigerator

solubility 

Chloroform, Ethyl Acetate, Methanol

form 

Liquid

color 

Colorless

Sensitive 

Moisture Sensitive

BRN 

1737682

CAS DataBase Reference

1850-14-2(CAS DataBase Reference)

NIST Chemistry Reference

Tetramethoxymethane(1850-14-2)

Safety Information

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-37

RIDADR 

UN 3272 3/PG 2

WGK Germany 

3

F 

21

HS Code 

2909.19.6000

HazardClass 

3.1

PackingGroup 

II

MSDS

• Language:English Provider:Tetramethyl orthocarbonate
• Language:English Provider:SigmaAldrich

Tetramethoxymethane Usage And Synthesis

Description

Tetramethoxymethane can be usede in ?CO2 fixation, formation of orthocarbonates from diols and electrophilic introduction of an ester functionality.

Uses

Tetramethoxymethane has application within an electrolyte solution for the use of rechargeable lithium batteries. It has also been used as a reactant in the synthesis of novel anti-HIV-1 compounds.

Synthesis

Tetramethoxymethane has been prepared by heating a solution of Sodium Methoxide in methanol with chloropicrin, Trichloroacetonitrile, or thiocarbonyl perchlorate; the best yields have been obtained with the perchlorate. Alternatively, disodium hexamethoxystannate (prepared in situ from sodium methoxide and tetrachlorostannane) can be refluxed with Carbon Disulfide in methanol to form the orthocarbonate.

Purification Methods

Tetramethyl orthocarbonate (methyl orthocarbonate, tetramethoxy methane) [1850-14-2] M 136.2, m -5.6o, -5o, -2o, b 113.5o/760mm, 113.5 -114o/755mm, 112-114o/atm, d 4 1.0202, n D 1.3860. Purify it in the same way as for tetraethyl orthocarbonate. [Smith Acta Chem Scand 10 1006 1956, Tiekelmann & Post J Org Chem 13 266 1948, Kantlehner et al. Synthesis 73 1977, Beilstein 3 IV 4.]

Tetramethoxymethane(1850-14-2)Related Product Information

• Trimethoxymethane
• Lithium carbonate
• Triethyl orthobenzoate
• Triethyl orthoacetate
• 1,1,1-Trimethoxypentane
• Dimethyl carbonate
• Calcium carbonate
• Polycarbonate
• Trimethyl orthoacetate
• Sodium bicarbonate
• Tetraethyl orthocarbonate
• Triethyl orthobutyrate
• TETRA-N-PROPOXYMETHANE
• Emetine dihydrochloride
• Tetramethoxymethane
• TETRAMETHYL-O-CARBONATE = TETRAMETHOXYMETHANE ()
• TETRAKIS(2,2,3,3,4,4,5,5-OCTAFLUOROPENTYL)ORTHOCARBONATE
• TETRAKIS(2,2,3,3-TETRAFLUOROPROPYL)ORTHOCARBONATE