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(S)-(+)-3-Quinuclidinol

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(S)-(+)-3-Quinuclidinol Basic information

Product Name:
(S)-(+)-3-Quinuclidinol
Synonyms:
  • (3S)-Quinuclidin-3-ol
  • 1-Azabicyclo[2.2.2]octan-3-ol, (3S)-
  • Solifenacin Succinate interMediate B
  • (S)-(+)-3-QUINUCLIDINOL
  • S-(+)-3-HYDROXY QUINUCLIDINE
  • (S)-3-Quinuclidinol. Hydrochloride
  • (S)-(+)-3-Hydroxy quinuclidine ,98%
  • (S)-quinuclidin-3-ol
CAS:
34583-34-1
MF:
C7H13NO
MW:
127.18
Mol File:
34583-34-1.mol
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(S)-(+)-3-Quinuclidinol Chemical Properties

Melting point:
215-217 °C
Boiling point:
206.9±23.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Aqueous Acid (Slightly), Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
14.75±0.20(Predicted)
color 
White to Off-White
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Safety Information

Safety Statements 
24/25
HS Code 
29349990
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(S)-(+)-3-Quinuclidinol Usage And Synthesis

Chemical Properties

Off-white crystalline powder

Uses

(3S)-1-Azabicyclo[2.2.2]octan-3-ol is an intermediate in the synthesis of Solifenacin Hydrochloride (S676700), a muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence. Also used in the synthesis of new anticholinergenic drugs such as penehyclidine hydrochloride.

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