Timosaponin A-III Chemical Properties

Melting point:

317-322 °C

Boiling point:

862.8±65.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

solubility 

DMF: 30 mg/ml; DMSO: 30 mg/ml

form 

White to off white solid.

pka

12.85±0.70(Predicted)

color 

White to off-white

Timosaponin A-III Usage And Synthesis

Uses

Timosaponin A3 suppresses certain human tumor processes and has the potential to be developed as an anticancer agent. Reverses multi-drug resistance in human chronic myelogenous leukemia K562/ADM cells via downregulation of MDR1 and MRP1 expression by inhibiting PI3K/Akt signaling pathway. Induction of mitochondrial-dependent apoptosis in HepG2 human hepatocellular carcinoma cells.Timosaponin A3 is a potent inhibitor of U46619, that induces rat platelet aggregation and exhibited superior selectivity for the TP receptor vs. other G protein-coupled receptors and a PKC activator.

Timosaponin A-III(41059-79-4)Related Product Information

• Sarsasapogenin
• Baicalin
• Honokiol
• Dioscin
• Escin
• Ginsenoside Rh2
• Saponin
• Sarsasapogenin
• Geniposide
• anemarsaponin B
• pseudoprototimosaponin AIII
• Anemarsaponin C
• DARUTIGENOL
• Valtrate
• Geraniol
• (R,10E)-4,8,9,12-Tetrahydro-3,11-dimethyl-6H-4,7-methenofuro[3,2-c]oxacycloundecin-6-one
• Anemarrhenasaponin-I
• Timosaponin BII