ETHYL 3-(N-METHYLAMINO) PROPIONATE Chemical Properties

Boiling point:

242.49°C (rough estimate)

Density 

1.0070

refractive index 

1.4443 (estimate)

storage temp. 

Inert atmosphere,Store in freezer, under -20°C

solubility 

Chloroform (Sparingly), Ethyl Acetate (Slightly)

form 

Oil

pka

9.55±0.10(Predicted)

color 

Colourless

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

HS Code 

2922498590

ETHYL 3-(N-METHYLAMINO) PROPIONATE Usage And Synthesis

Uses

Ethyl N-Methyl-beta-alaninate is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension.

Synthesis Reference(s)

Journal of the American Chemical Society, 71, p. 2124, 1949 DOI: 10.1021/ja01174a061

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