Basic information Safety Supplier Related

Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)-

Basic information Safety Supplier Related

Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)- Basic information

Product Name:
Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)-
Synonyms:
  • Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)-
  • α-Glucosidase-IN-6
CAS:
2497685-29-5
MF:
C24H17ClF3NO3S
MW:
491.91
Mol File:
2497685-29-5.mol
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Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)- Chemical Properties

Boiling point:
614.7±65.0 °C(Predicted)
Density 
1.401±0.06 g/cm3(Predicted)
pka
6.45±0.10(Predicted)
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Benzenesulfonamide, N-[4-[5-(4-chlorophenyl)-1-oxo-2,4-pentadien-1-yl]phenyl]-4-(trifluoromethyl)- Usage And Synthesis

Uses

α-Glucosidase-IN-6 (compound 18) is a competitive α-glucosidase inhibitor with an IC50 of 5.69 μM. α-Glucosidase-IN-6 has anti-diabetic potential[1].

References

[1] Maryam Aisyah Abdullah, et al. Development of diarylpentadienone analogues as alpha-glucosidase inhibitor: Synthesis, in vitro biological and in vivo toxicity evaluations, and molecular docking analysis. Bioorg Chem. 2020 Nov;104:104277. DOI:10.1016/j.bioorg.2020.104277

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