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savinin

Basic information Safety Supplier Related

savinin Basic information

Product Name:
savinin
Synonyms:
  • savinin
  • (-)-Hibalactone
  • (4R)-4,5-Dihydro-4-(1,3-benzodioxole-5-ylmethyl)-3-[(E)-1,3-benzodioxol-5-ylmethylene]furan-2(3H)-one
  • (R)-4,5-Dihydro-4-(1,3-benzodioxol-5-ylmethyl)-3-[(E)-1,3-benzodioxol-5-ylmethylene]furan-2(3H)-one
  • Hibalactone
  • 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylene)dihydro-, (3E,4R)-
  • (3E,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-(1,3-benzodioxol-5-ylmethylidene)oxolan-2-one
  • AI 3-26464
CAS:
493-95-8
MF:
C20H16O6
MW:
352.34
Mol File:
493-95-8.mol
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savinin Chemical Properties

Melting point:
146.4-148.4 °C(Solv: benzene (71-43-2))
Boiling point:
573.5±39.0 °C(Predicted)
Density 
1.439±0.06 g/cm3(Predicted)
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savinin Usage And Synthesis

Uses

Hibalactone is a plant terpenoid and lignoid which possess potent antiviral activities against severe acute respiratory syndrome Coronavirus.

Definition

ChEBI: Savinin is a lignan that is dihydrofuran-2(3H)-one (gamma-butyrolactone) substituted by a 1,3-benzodioxol-5-ylmethylidene group at position 3 and a 1,3-benzodioxol-5-ylmethyl group at position 4 (the 3E,4R-isomer). It exhibits antiviral activity against SARS-CoV-2. It has a role as a T-cell proliferation inhibitor, an anti-inflammatory agent, a plant metabolite, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor and an anticoronaviral agent. It is a member of benzodioxoles, a lignan and a gamma-lactone.

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