ISOEGOMAKETONE
ISOEGOMAKETONE Basic information
- Product Name:
- ISOEGOMAKETONE
- Synonyms:
-
- ISOEGOMAKETONE
- (E)-1-(furan-3-yl)-4-methylpent-2-en-1-one
- 2-Penten-1-one, 1-(3-furanyl)-4-methyl-, (2E)-
- CAS:
- 34348-59-9
- MF:
- C10H12O2
- MW:
- 164.2
- Mol File:
- 34348-59-9.mol
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ISOEGOMAKETONE Chemical Properties
- Boiling point:
- 70 °C(Press: 1 Torr)
- Density
- 1.002±0.06 g/cm3(Predicted)
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ISOEGOMAKETONE Usage And Synthesis
Definition
ChEBI: Isoegomaketone is an aromatic ketone.
Synthesis Reference(s)
Synthesis, p. 991, 1984 DOI: 10.1055/s-1984-31051
Anticancer Research
This compound tested in in vivo models of B16 melanoma gave a significant cellgrowth inhibition. The tumor cells show an ROS-mediated mitochondria-dependentapoptotic-type death in sub-G1 cell cycle. Iso-egomaketone seemed to generateROS in cells as well as upregulation of Bax and Bcl-2expression (Russo et al. 2015;Shen et al. 2012).
ISOEGOMAKETONESupplier
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