Ajugol Chemical Properties

Boiling point:

617.9±55.0 °C(Predicted)

Density 

1.57

storage temp. 

Store at -20°C

solubility 

DMSO : ≥ 3.7 mg/mL (10.62 mM)

pka

12.80±0.70(Predicted)

form 

Solid

color 

White to off-white

InChI

InChI=1/C15H24O9/c1-15(21)4-7(17)6-2-3-22-13(9(6)15)24-14-12(20)11(19)10(18)8(5-16)23-14/h2-3,6-14,16-21H,4-5H2,1H3/t6-,7+,8+,9+,10+,11-,12+,13-,14-,15-/s3

InChIKey

VELYAQRXBJLJAK-HWRKDDHMNA-N

SMILES

O([C@]1([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@@H]1OC=C[C@@]2([H])[C@H](O)C[C@@](O)(C)[C@@]12[H] |&1:1,4,7,9,11,13,17,19,22,25,r|

Ajugol Usage And Synthesis

Chemical Properties

Pale yellow powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Rehmannia root.

Uses

Ajugol is an iridoid glycoside that can be isolated from Leonurus artemisia. Ajugol has anti-protozoal activity againt Trypanosoma b. rhodesiense with an IC50 of 31.8 μg/mL[1].

IC 50

Trypanosoma

References

[1] Deniz Tasdemir, et al. Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots. Phytochemistry. 2005 Feb;66(3):355-62. DOI:10.1016/j.phytochem.2004.11.013

Ajugol(52949-83-4)Related Product Information

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