4-Chlorophenoxyacetic acid Chemical Properties

Melting point:

157-159 °C

Boiling point:

266.91°C (rough estimate)

Density 

1.3245 (rough estimate)

refractive index 

1.5250 (estimate)

storage temp. 

Sealed in dry,Room Temperature

solubility 

957mg/l

form 

crystalline

pka

pK1: 3.10 (25°C)

color 

White to light beige

Water Solubility 

848mg/L(25 ºC)

BRN 

1211804

LogP

2.250

CAS DataBase Reference

122-88-3(CAS DataBase Reference)

NIST Chemistry Reference

4-Chlorophenoxyacetic acid(122-88-3)

EPA Substance Registry System

4-Chlorophenoxyacetic acid (122-88-3)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-R22

Safety Statements 

22-24/25

RIDADR 

2811

WGK Germany 

1

RTECS 

AG0175000

F 

21

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29189090

Hazardous Substances Data

122-88-3(Hazardous Substances Data)

Toxicity

LD50 oral in rat: 850mg/kg

MSDS

• Language:English Provider:4-CPA
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Chlorophenoxyacetic acid Usage And Synthesis

Chemical Properties

white to light beige powder

Uses

4-chlorophenoxy acetic acid (4-CPA), a chlorine derivative of phenoxyacetic acid (PA), is a plant growth regulator used as a herbicide.

Uses

2-(4-Chlorophenoxy)acetic Acid is used in the synthesis of a new class of hypoxia-inducible factor-1 inhibitors.

Definition

ChEBI: A chlorophenoxyacetic acid that is phenoxyacetic acid carrying a chloro substituent at position 4.

General Description

4-Chlorophenoxyacetic acid is a herbicide. Degradation of 4-chlorophenoxyacetic acid in aqueous medium by advanced electrochemical oxidation processes, using an undivided cell containing a Pt anode has been reported.

Hazard

Moderately toxic; mutagen.

Biochem/physiol Actions

4-Chlorophenoxyacetic acid is a synthetic auxin, that is used to induce parthenocarpic ovary growth on flowers of wild type plants.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl-.

Purification Methods

Crystallise the acid from EtOH. It is a plant growth substance and a herbicide. [Beilstein 6 IV 845.]

4-Chlorophenoxyacetic acid(122-88-3)Related Product Information

• 2-(4-Chlorophenoxy)-2-methylpropionic acid
• 2-Chlorophenylacetic acid
• phenoxybenzamine
• ​4-Chlorophenoxyacetic acid sodium salt
• 2,4-Dichlorophenoxyacetic acid
• Phenoxyacetic acid
• 4-Chlorophenylacetic acid
• Fluroxypyr
• Allyl phenoxyacetate
• Triclopyr
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-Chlorostyrene
• 4-Chlorobenzyl cyanide
• 4-CHLOROPHENETOLE
• 4'-Chloroacetophenone
• Phenylacetic acid
• Dichlorprop
• 2,4,5-Trichlorophenoxyacetic acid