Fluroxypyr Chemical Properties

Melting point:

57.5°C

Boiling point:

399.4±37.0 °C(Predicted)

Density 

1.3

storage temp. 

Sealed in dry,2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

2.22±0.10(Predicted)

color 

White to Off-White

Merck 

13,4229

BRN 

7136185

LogP

3.160 (est)

CAS DataBase Reference

69377-81-7(CAS DataBase Reference)

NIST Chemistry Reference

Fluroxypyr(69377-81-7)

EPA Substance Registry System

Fluroxypyr (69377-81-7)

Safety Information

Risk Statements 

52/53

Safety Statements 

61

RIDADR 

UN3077(solid)

WGK Germany 

2

RTECS 

AF2500000

Hazardous Substances Data

69377-81-7(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 2405 mg/kg; i.p. in male, female rats: 458, 519 mg/kg; percutaneous in rabbits >5000 mg/kg (Paul)

Fluroxypyr Usage And Synthesis

Chemical Properties

White crystalline solid.

Uses

Fluroxypyr is a systemic and selective herbicide. Fluroxypyr is used for the control of broad-leaved weeds in small grain cereals, maize, pastures, range land and turf. Fluroxypyr is a synthetic auxin.

Definition

ChEBI: An aminopyridine that is pyridin-4-amine substituted by chloro groups at positions 3 and 5, a fluoro group at position 6 and a carboxymethoxy group at position 2.

Trade name

methyl ester: AGROSTAR; BOFIX FFC®; CABADEX®; CASCADE®; DOWCO® 433 MHE; FOREFRONT®; GALAXY GL184®; PARADIGM®; PASTUREGARD®; STARANE®; TOMAHAWK®; VISTA®; WIDEMATCH®, (fluroxypyr + clopyralid); XRM-5084®

Potential Exposure

Those who manufacture, distribute or use this pyridinecarboxylic acid/pyridine herbicide.

Environmental Fate

The DT₅₀ in soil is relatively short, ranging from 5 to 9 days in experiments conducted in the laboratory. This rapid degradation is due to microbes.Because of its rapid soil degradation, little fluroxypyr is available for other dissipation processes, e.g., leaching.

Metabolism

Fluroxypyr is stable under acidic conditions and moderately stable in alkaline conditions; e.g., the DT₅₀ in water at pH 9 is 185 days. Degradation occurs at temperatures above its melting point. Fluroxypyr is stable in light.
Plant. The metabolism of fluroxypyr has not been fully described. Conjugates of fluroxypyr have been observed in tolerant plants.
Soil. Fluroxypyr is rapidly metabolized by soil microbes via the removal of the carboxyl group or acetic acid group, yielding 4-amino-3,5-dichloro-6-fluoro- 2-methoxypyridine, and 4-amino-3,5-dichloro-6-fluoro-2- pyridinol, respectively.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz ardous material, Technical Name Required.

Toxicity evaluation

Mammalian Toxicity. Fluroxypyr appears to be rapidly excreted, unmodified, in the urine of animals. The acute oral LD₅₀ for rat is 2405 mg/kg.
Weed Resistance/Modified Crop Tolerance. Fuerst et al. (48) reported fluroxypyr resistance in yellow starthistle (Centaurea solstitialis). No crops with modified tolerance toward fluroxypyr are currently in production.

Incompatibilities

May not be compatible with nitrates. Moisture may cause hydrolysis or other forms of decompo sition; forming a strong acid. Temperatures above 250℃ can cause decomposition. Methyl ester: Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is suffi ciently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solu tions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Waste Disposal

Containers must be disposed of properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an after burner and scrubber. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesti cide containers.

Fluroxypyr(69377-81-7)Related Product Information

• Glycine
• Sodium dichloroacetate
• Methyl chloroacetate
• Trifluoroacetic acid
• Ethyl chloroacetate
• Allyl phenoxyacetate
• Dichloroacetic acid
• Clopyralid
• Ethyl acetate
• Ethyl 2-(Chlorosulfonyl)acetate
• Ethyl bromodifluoroacetate
• Phenoxyacetic acid
• 3-Aminopyridine
• Trifluoroacetic anhydride
• Iminodiacetic acid
• 2-Aminopyridine
• ALTRENOGEST
• Triclopyr