WSP-1 Chemical Properties

Boiling point:

769.9±60.0 °C(Predicted)

Density 

1.51±0.1 g/cm3(Predicted)

storage temp. 

Store at -20°C, protect from light

solubility 

DMF: 20 mg/ml; DMSO: 2 mg/ml

form 

A crystalline solid

pka

1.39±0.19(Predicted)

color 

White to off-white

WSP-1 Usage And Synthesis

Description

Hydrogen sulfide (H₂S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H₂S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H₂S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.¹

References

1. Liu, C., Pan, J., Li, S., et al. Capture and visualization of hydrogen sulfide via a fluorescent probe Angew. Chem. Int. Ed. Engl. 50(44),10327-10329(2011).

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