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PENTACOSANOIC ACID

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PENTACOSANOIC ACID Basic information

Product Name:
PENTACOSANOIC ACID
Synonyms:
  • PENTACOSANOIC ACID
  • N-PENTACOSANOIC ACID
  • N-PENTACOSANOIC ACID 95+%
  • PENTACOSANOIC ACID(SG)
  • Pentacosanoic aci
  • NSC 89289
  • Pentacosanoic
  • PentacosanoicAcid>
CAS:
506-38-7
MF:
C25H50O2
MW:
382.66
EINECS:
208-036-0
Product Categories:
  • Biochemistry
  • Higher Fatty Acids & Higher Alcohols
  • Monofunctional & alpha,omega-Bifunctional Alkanes
  • Monofunctional Alkanes
  • Saturated Higher Fatty Acids
  • Fatty Acids
  • Saturated fatty acids and derivatives
  • Straight chain fatty acids
  • Alkylcarboxylic Acids
Mol File:
506-38-7.mol
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PENTACOSANOIC ACID Chemical Properties

Melting point:
83 °C
Boiling point:
440.48°C (rough estimate)
Density 
0.8913 (rough estimate)
refractive index 
1.4675 (estimate)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
4.78±0.10(Predicted)
color 
White
CAS DataBase Reference
506-38-7(CAS DataBase Reference)
EPA Substance Registry System
Pentacosanoic acid (506-38-7)
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Safety Information

HS Code 
2915.90.1800
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PENTACOSANOIC ACID Usage And Synthesis

Uses

Pentacosanoic Acid is a saturated fatty acid.

Definition

ChEBI: Pentacosanoic acid is a straight-chain saturated fatty acid and a very long-chain fatty acid. It is a conjugate acid of a pentacosanoate.

in vivo

The degree of demyelination in adrenoleukodystrophy is related to the Pentacosanoic to Docosanoic acid ratios (C25:0/C22:0 and C26:0/C22:0). Mainly saturated fatty acids of the middle class components (C24:0, C25:0 and C26:0) are found in severely affected areas where the active process is complete. Because a region of high long chain fatty acid content, lacking histopathological change, is detected[1].
The area with myelin destruction with axonal preservation is generally most prominent in the frontal edge of the lesion. A bell-shaped distribution of very long chain fatty acids, esterified to cholesterol, are detectable, with the mid-point being formed by Pentacosanoic (C25 : 0) and Hexacosanoic (C26 : 0) acids[1].

IC 50

Human Endogenous Metabolite

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