Basic information Safety Supplier Related

(R)-AMbrisentan

Basic information Safety Supplier Related

(R)-AMbrisentan Basic information

Product Name:
(R)-AMbrisentan
Synonyms:
  • (R)-AMbrisentan
  • (2R)-2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
  • Ambrisentan Impurity 5
  • Benzenepropanoic acid, α-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-, (αR)-
CAS:
1007358-76-0
MF:
C22H22N2O4
MW:
378.43
Mol File:
1007358-76-0.mol
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(R)-AMbrisentan Chemical Properties

Melting point:
>161°C (dec.)
Boiling point:
551.1±60.0 °C(Predicted)
Density 
1.228±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Sparingly, Heated, Sonicated)
form 
Solid
pka
0.97±0.10(Predicted)
color 
White to Off-White
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(R)-AMbrisentan Usage And Synthesis

Uses

(R)-Ambrisentan is the R-isomer impurity of Ambrisentan (A575860), which is a nonpeptide endothelin ETA receptor antagonist. Antihypertensive.

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(R)-AMbrisentan(1007358-76-0)Related Product Information