1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE Chemical Properties

Melting point:

209 °C

Density 

2.04±0.1 g/cm3 (20 ºC 760 Torr)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

DMSO: >20mg/mL

form 

solid

pka

12.68±0.70(Predicted)

color 

white

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

HS Code 

2933.99.8290

1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE Usage And Synthesis

Uses

2-Cl-IB-MECA acts as an A3 adenosine receptor-selective nucleoside.

Biological Activity

High affinity and extremely selective A 3 adenosine receptor agonist (K i = 0.33 nM). Displays 2500- and 1400-fold selectivity over A 1 and A 2A receptors respectively. Exhibits high selectivity over the Na + -independent adenosine transporter.

storage

Desiccate at +4°C

1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE(163042-96-4)Related Product Information

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• 1-[2-CHLORO-6-[[(3-IODOPHENYL)METHYL]AMINO]-9H-PURIN-9-YL]-1-DEOXY-N-METHYL-BETA-D-RIBOFURANURONAMIDE
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• 2-chloro-9-methyl-9H-purine
• 5'-AMINOADENOSINE
• adenosine 5'-carboxamide