Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Chemical Reagents >  Organic reagents >  fatty acid >  L-LEUCIC ACID

L-LEUCIC ACID

Basic information Safety Supplier Related

L-LEUCIC ACID Basic information

Product Name:
L-LEUCIC ACID
Synonyms:
  • (s)-pentanoicaci
  • (S)-(-)-2-HYDROXYISOCAPROIC ACID
  • (S)-2-HYDROXY-4-METHYLVALERIC ACID
  • 2-HYDROXY-3-METHYLVALERIC ACID
  • 2-HYDROXY-3-METHYLPENTANOIC ACID
  • L-2-hydroxy-4-methylvaleric acid
  • LEUCIC ACID
  • L-LEUCIC ACID
CAS:
13748-90-8
MF:
C6H12O3
MW:
132.16
EINECS:
237-329-6
Product Categories:
  • API intermediates
  • Carboxylic Acids (Chiral)
  • chiral
  • Chiral Building Blocks
  • Synthetic Organic Chemistry
Mol File:
13748-90-8.mol
More
Less

L-LEUCIC ACID Chemical Properties

Melting point:
78-80 °C(lit.)
Boiling point:
277.83°C (rough estimate)
Density 
1.0160 (rough estimate)
refractive index 
-26 ° (C=2, 1 %NaOH)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Aqueous Base (Slightly), DMSO (Sparingly), Water (Slightly)
form 
Solid
pka
3.86±0.21(Predicted)
color 
White to Off-White
optical activity
[α]22/D 26.3°, c = 1 in 1 M NaOH
Water Solubility 
almost transparency
LogP
0.710
CAS DataBase Reference
13748-90-8(CAS DataBase Reference)
EPA Substance Registry System
Pentanoic acid, 2-hydroxy-4-methyl-, (2S)- (13748-90-8)
More
Less

Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29181990

MSDS

More
Less

L-LEUCIC ACID Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

L-Leucic Acid is a reagent in the synthesis of cryptophycins based macrocyclic depsipeptides which are used as tubulin inhibitors.

Definition

ChEBI: The (S)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Derived from the metabolism of the branched-chain amino acids, it belongs to the 2-hydroxycarboxylic acid group of amino acid metabolites.

L-LEUCIC ACIDSupplier

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Email
jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Email
market03@meryer.com
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Email
Sales-CN@TCIchemicals.com
Chang Zhou Chemistar Chemistry Technology Co.,Ltd
Tel
+86 (519) 8689-6136
Email
kr@krchemistar.com
Energy Chemical
Tel
021-021-58432009 400-005-6266
Email
sales8178@energy-chemical.com