Disodium succinate Chemical Properties

Melting point:

>300°C

Density 

1.46 g/cm3

FEMA 

3277 | DISODIUM SUCCINATE

storage temp. 

Store below +30°C.

solubility 

350g/l

form 

Crystalline Powder

color 

White

PH

7-9 (100g/l, H2O, 20℃)

Odor

odorless

Odor Type

odorless

biological source

synthetic

Water Solubility 

300 g/L (25 ºC)

Merck 

13,8754

BRN 

3917246

Major Application

flavors and fragrances

Cosmetics Ingredients Functions

SURFACTANT - CLEANSING
FRAGRANCE

Cosmetic Ingredient Review (CIR)

Disodium succinate (150-90-3)

InChI

1S/C4H6O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H2,(H,5,6)(H,7,8);;/q;2*+1/p-2

InChIKey

ZDQYSKICYIVCPN-UHFFFAOYSA-L

SMILES

[Na+].[Na+].[O-]C(=O)CCC([O-])=O

LogP

-0.59

CAS DataBase Reference

150-90-3(CAS DataBase Reference)

NIST Chemistry Reference

Sodium succinate(150-90-3)

EPA Substance Registry System

Butanedioic acid, sodium salt (1:2) (150-90-3)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-24/25

WGK Germany 

1

RTECS 

WM7751000

F 

3

TSCA 

TSCA listed

HS Code 

29171990

Storage Class

11 - Combustible Solids

Toxicity

LD50 i.v. in mice: 4.5 g/kg (Zuckerbrod, Graef)

MSDS

• Language:English Provider:Butanedioic acid disodium salt
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

Disodium succinate Usage And Synthesis

Chemical Properties

Disodium succinate, also known as sodium succinate, white crystalline particle, odorless, not deliquescent in the air; soluble in water, and insoluble in organic solvents. Aqueous solution has a shellfish fresh flavor and no acidic taste. It can be used as a food flavoring agent, acidifier, or buffering agent.

Uses

Succinic acid disodium salt is used to prepare buffer solution for the quantitative analysis of auxins.
It can be also used:
    To study the effect of liquid phase on the basic properties of α-tricalcuim phosphate (α-TCP) based cement, BIOPEX.
    In the synthesis of cadmium sulfide (CdS) nanoparticles using thiourea as a source for sulfide.

Definition

ChEBI: Sodium succinate (anhydrous) is a sodium salt that is the disodium salt of succinic acid. The hexahydrate form is used as an ingredient of topical preparations for the treatment of cataract. It contains a succinate(2-).

Preparation

Disodium succinate is produced by neutralizing succinic acid with sodium hydroxide. The anhydrous material is then dried at 120°C in hot air and pulverized to obtain.

General Description

Disodium succinate is used in the food industry as an acidity regulator and flavor enhancer.

Flammability and Explosibility

Not classified

Toxicology

The oral LD₅₀ value for disodium succinate is > 1,200 mg/kg bw (Rat). The no-observed-adverse-effect level (NOAEL) for repeated-dose toxicity was 60 mg/kg body weight/day in male rats and 180 mg/kg body weight/day in female rats. No mutagenicity was observed. No reproductive or developmental toxicity was observed at daily doses of up to 600 mg/kg body weight.

Source

Disodium succinate (WSA), was found with high content in scallops, and it contributes to important umami taste in seafoods, such as shellfish, shrimp and crab. Moreover, WSA has also been discovered as the important umami contributor in shiitake mushrooms . The taste threshold of WSA is 0.03%(w/v), with a special shellfish taste . According to the Chinese Food Additives Standard, WSA is the only organic acid umami contributor that is allowed in food products such as meat products, aquatic products and sauces[1].

Purification Methods

Crystallise it twice from water (1.2mL/g) and dry it at 125o. It has been freed from other metal ions by passage of a 0.1M solution through a column of Dowex resin A-1 (Na form). It is hygroscopic. [Beilstein 2 H 606, 2 IV 1908.]

References

[1] Jie Ma . (2020). Quantitative analyses of the umami characteristics of disodium succinate in aqueous solution. Food Chemistry, 316, Article 126336. https://doi.org/10.1016/j.foodchem.2020.126336

Disodium succinate(150-90-3)Related Product Information

• Succinic anhydride
• Succinic acid
• Diethyl succinate
• Ethylenediaminetetraacetic acid disodium salt
• L-ASPARTIC ACID
• Folic acid
• Butanedihydrazide
• Dimethyl succinate
• DL-Malic acid
• Succimer
• Sodium Monofluorophosphate
• Dioctyl sulfosuccinate sodium salt
• ZINC ZIRCONATE
• DODECENYLSUCCINIC ACID
• Citric acid
• Ascoric Acid
• 6alpha-Methylprednisolone sodium succinate
• AEROSOL 22
• Succinic Acid Disodium Salt