6alpha-Methylprednisolone sodium succinate CAS#: 2375-03-3

6alpha-Methylprednisolone sodium succinate Basic information

Product Name:

6alpha-Methylprednisolone sodium succinate

Synonyms:

(6alpha,11beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-pregna-1,4-diene-3,20-dione monosodium salt
6ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE 21-HEMISUCCINATE SODIUM SALT
6ALPHA-METHYLPREDNISOLONE 21-HEMISUCCINATE SODIUM SALT
6-ALPHA-METHYLPREDNISOLONE SODIUM SUCCINATE
1,4-PREGNADIEN-6-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE 21-SUCCINATE, SODIUM SALT
6α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate
6α-methylprednisolone 21-hemisuccinate sodium salt
Methylprednisolone sodium succinate (JAN/USP)

CAS:

2375-03-3

MF:

C26H33O8.Na

MW:

496.53

EINECS:

219-156-8

Mol File:

2375-03-3.mol

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6alpha-Methylprednisolone sodium succinate Chemical Properties

Melting point:: >186°C (dec.)
storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: lyophilized powder
color: White to Off-White
CAS DataBase Reference: 2375-03-3(CAS DataBase Reference)

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Safety Information

Hazard Codes: T
Risk Statements: 61-40
Safety Statements: 53-22-36/37/39-45
WGK Germany: 3
RTECS: TU4154060
Toxicity: LD50 oral in rat: > 5gm/kg

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6alpha-Methylprednisolone sodium succinate Usage And Synthesis

Uses

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.

Uses

6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries.

Definition

ChEBI: Methylprednisolone sodium succinate is a corticosteroid hormone.

brand name

A-Methapred (Abbott); A-Methapred (Hospira); Solu-Medrol (Pharmacia & Upjohn).

Biochem/physiol Actions

Glucocorticoid with slightly longer half-life than that of prednisolone.

6alpha-Methylprednisolone sodium succinateSupplier

Wuhan Jingkangen Biomedical Technology Co., Ltd Gold

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Spectrum Chemical Manufacturing Corp.

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Email: marketing_china@spectrumchemical.com

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