Basic information Safety Supplier Related

LOXO-195

Basic information Safety Supplier Related

LOXO-195 Basic information

Product Name:
LOXO-195
Synonyms:
  • LOXO-195
  • (18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one
  • Selitrectinib Racemate
  • (6RS)-LOXO-195
  • Selitrectinib(LOXO-195) Racemate
  • 12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
  • LOXO195 R racemic
  • LOXO-195(3aR)
CAS:
1350884-56-8
MF:
C20H21FN6O
MW:
380.42
Mol File:
1350884-56-8.mol
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LOXO-195 Chemical Properties

Density 
1.51±0.1 g/cm3(Predicted)
pka
11.44±0.40(Predicted)
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LOXO-195 Usage And Synthesis

Description

LOXO-195 is an orally available, highly potent, and selective TRK kinase inhibitor designed to overcome drug resistance mediated by acquired mutations. Although responses to TRK inhibition can be dramatic and durable; however, eventually emergence of acquired resistance is found to be inevitable.

LOXO-195Supplier

Shanghai Changyu Medical Technology Co. Ltd. Gold
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+86-13301875428
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Shanghai YuanQi Biotechnology Co., Ltd.
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+86-2332782371 +86-18120098618
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sales@adobechem.com
Guangzhou Zhiya Chemdrugs Co.,Ltd
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18122150900
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sculk28@163.com
Shanghai Changyan Chem & Tech Co., Ltd.
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021-20242659 18930833303
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Sales@changyanchem.cn
Shanghai Rechem science Co., Ltd.
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21-31433387 15618786686
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sales@rechemscience.com
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