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Posaconazole Impurity 48

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Posaconazole Impurity 48 Basic information

Product Name:
Posaconazole Impurity 48
Synonyms:
  • 4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)
  • posaconazole N-Oxide impurity 3
  • Posaconazole Impurity 48
  • Posaconazole 1-Oxido Impurity
  • D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-4-oxido-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-
  • 4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazine 1-oxide
  • 4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)-1-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazine 1-oxide (Posaconazole Impurity)
  • Posaconazole Piperazine N4-Oxide
CAS:
1902954-03-3
MF:
C37H42F2N8O5
MW:
716.79
Mol File:
1902954-03-3.mol
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Posaconazole Impurity 48 Chemical Properties

solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
14.72±0.20(Predicted)
form 
Solid
color 
Off-White
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Posaconazole Impurity 48 Usage And Synthesis

Uses

Posaconazole Mono N-Oxide is a degradation product of Posaconazole (P689600), which is an orally active triazole antifungal.

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