Axitinib Impurity 27 CAS#: 1639137-80-6

Axitinib Impurity 27

Basic information Safety Supplier Related

Product Name:

Axitinib Impurity 27

Synonyms:

Axitinib Impurity 27
Axitinib Impurity 11/(E)-2-((1-acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide
N-Acetyl Axitinib
Benzamide, 2-[[1-acetyl-3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-N-methyl-
Axitinib J
(E)-2-((1-Acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide (Axitinib Impurity)
(E)-2-((1-acetyl-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)-N-methylbenzamide
2-({1-Acetyl-3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)-N-methylbenzamide

CAS:

1639137-80-6

MF:

C24H20N4O2S

MW:

428.51

Mol File:

1639137-80-6.mol

Less

Melting point:: 214 - 215°C
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: 4°C, Inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 14.42±0.46(Predicted)
form: Solid
color: Light Yellow to Yellow
InChI: InChI=1S/C24H20N4O2S/c1-16(29)28-22-15-18(31-23-9-4-3-8-20(23)24(30)25-2)11-12-19(22)21(27-28)13-10-17-7-5-6-14-26-17/h3-15H,1-2H3,(H,25,30)/b13-10+
InChIKey: DPCLTPPDTUVUIL-JLHYYAGUSA-N
SMILES: C(NC)(=O)C1=CC=CC=C1SC1=CC2=C(C=C1)C(/C=C/C1=NC=CC=C1)=NN2C(C)=O

Less

N-Acetyl Axitinib is an intermediate used in the synthesis of Axitinib. Axitinib is a tyrosine kinase inhibitor that is also used in cancer therapy.

Adamas Reagent, Ltd.

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Shanghai Kewel Chemical Co., Ltd.

Shanghai SuperLan Chemcial Technique Centre

Hubei Yangxin Medical Technology Co., Ltd.

Less