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FMOC-6-AMINOHEXANOIC ACID

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FMOC-6-AMINOHEXANOIC ACID Basic information

Product Name:
FMOC-6-AMINOHEXANOIC ACID
Synonyms:
  • FMOC-NH-(CH2)5-COOH
  • FMOC-AMINOCAPROIC ACID
  • FMOC-AHX(6)-OH
  • FMOC-ACP-OH
  • FMOC-ACP(6)-OH
  • FMOC-6-ACA-OH
  • FMOC-6-AHX-OH
  • FMOC-6-AMINOCAPROIC ACID
CAS:
88574-06-5
MF:
C21H23NO4
MW:
353.41
Product Categories:
  • Unusual Amino Acids
  • Amino Acid Derivatives
  • Amino Acids
Mol File:
88574-06-5.mol
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FMOC-6-AMINOHEXANOIC ACID Chemical Properties

Melting point:
114 °C
Boiling point:
582.7±33.0 °C(Predicted)
Density 
1.210±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in water or 1% acetic acid
form 
Powder
pka
4.75±0.10(Predicted)
color 
White
Water Solubility 
Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble.
BRN 
5883220
CAS DataBase Reference
88574-06-5(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
HS Code 
2924 29 70
HazardClass 
IRRITANT

MSDS

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FMOC-6-AMINOHEXANOIC ACID Usage And Synthesis

Description

Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.

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