FMOC-6-AMINOHEXANOIC ACID CAS#: 88574-06-5

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FMOC-6-AMINOHEXANOIC ACID

Basic information Safety Supplier Related

FMOC-6-AMINOHEXANOIC ACID Basic information

Product Name:

FMOC-6-AMINOHEXANOIC ACID

Synonyms:

FMOC-NH-(CH2)5-COOH
FMOC-AMINOCAPROIC ACID
FMOC-AHX(6)-OH
FMOC-ACP-OH
FMOC-ACP(6)-OH
FMOC-6-ACA-OH
FMOC-6-AHX-OH
FMOC-6-AMINOCAPROIC ACID

CAS:

88574-06-5

MF:

C21H23NO4

MW:

353.41

Product Categories:

Unusual Amino Acids
Amino Acid Derivatives
Amino Acids

Mol File:

88574-06-5.mol

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FMOC-6-AMINOHEXANOIC ACID Chemical Properties

Melting point:: 114 °C
Boiling point:: 582.7±33.0 °C(Predicted)
Density: 1.210±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in water or 1% acetic acid
form: Powder
pka: 4.75±0.10(Predicted)
color: White
Water Solubility: Soluble in 1% acetic acid, water and 1mmol in 2mL DMF clearly soluble.
BRN: 5883220
CAS DataBase Reference: 88574-06-5(CAS DataBase Reference)

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Safety Information

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 2924 29 70
HazardClass: IRRITANT

MSDS

Language:English Provider:SigmaAldrich

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FMOC-6-AMINOHEXANOIC ACID Usage And Synthesis

Description

Fmoc-6-aminohexanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-6-aminohexanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Properties

White powder

Uses

Fmoc-6-aminohexanoic acid, is an amino acid derivative used in chemical synthesis and peptide chemistry.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-6-AMINOHEXANOIC ACIDSupplier

J & K SCIENTIFIC LTD.

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