ChemicalBook > Product Catalog > Biochemical Engineering > Amino Acids and Derivatives > Glycine derivative > (RS)-3,5-DHPG
(RS)-3,5-DHPG
(RS)-3,5-DHPG Basic information
- Product Name:
- (RS)-3,5-DHPG
- Synonyms:
-
- DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE
- (RS)-3
- 2-amino-2-(3
- 5-dihydroxyphenyl)acetic acid
- 5-Dihydroxyphenylglycine
- (RS)-3,5-DHPG
- (RS)-3,5-DIHYDROXYPHENYLGLYCINE
- TOC(RS)-3-5DHPG
- CAS:
- 19641-83-9
- MF:
- C8H9NO4
- MW:
- 183.16
- Product Categories:
-
- Glutamate receptor
- Glutamate
- Mol File:
- 19641-83-9.mol
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(RS)-3,5-DHPG Chemical Properties
- Melting point:
- >181°C (Dec.)
- storage temp.
- Desiccate at -20°C
- solubility
- Acetonitrile (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble to 10 mM in water
- Stability:
- Hygroscopic
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(RS)-3,5-DHPG Usage And Synthesis
Uses
(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease.
Biological Activity
Selective group I metabotropic glutamate receptor agonist which activates both mGlu 1 and mGlu 5 . Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D.
(RS)-3,5-DHPGSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
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Ascent Scientific
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Shanghai EFE Biological Technology Co., Ltd.
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