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(RS)-3,5-DHPG

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(RS)-3,5-DHPG Basic information

Product Name:
(RS)-3,5-DHPG
Synonyms:
  • DL-ALPHA-(3,5-DIHYDROXYPHENYL)GLYCINE
  • (RS)-3
  • 2-amino-2-(3
  • 5-dihydroxyphenyl)acetic acid
  • 5-Dihydroxyphenylglycine
  • (RS)-3,5-DHPG
  • (RS)-3,5-DIHYDROXYPHENYLGLYCINE
  • TOC(RS)-3-5DHPG
CAS:
19641-83-9
MF:
C8H9NO4
MW:
183.16
Product Categories:
  • Glutamate receptor
  • Glutamate
Mol File:
19641-83-9.mol
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(RS)-3,5-DHPG Chemical Properties

Melting point:
>181°C (Dec.)
storage temp. 
Desiccate at -20°C
solubility 
Acetonitrile (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble to 10 mM in water
Stability:
Hygroscopic
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(RS)-3,5-DHPG Usage And Synthesis

Uses

(RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson''s disease.

Biological Activity

Selective group I metabotropic glutamate receptor agonist which activates both mGlu 1 and mGlu 5 . Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D.

(RS)-3,5-DHPGSupplier

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Ascent Scientific
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4401179829988
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customerservice@ascentscientific.co.uk
EMMX Biotechnology LLC
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888-539-0666
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Pharmacodia (Beijing) Co.,Ltd
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+86-400-851-9921
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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627
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info@efebio.com
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