VENTURICIDIN A
VENTURICIDIN A Basic information
- Product Name:
- VENTURICIDIN A
- Synonyms:
-
- a-130
- aa-0368
- venturicidinb,3’-carbamate
- HHQKNFDAEDTRJK-WLJINWSWSA-N
- 4,21-Dioxabicyclo[15.3.1]heneicosa-9,15,18-trien-3-one, 11-[[3-O-(aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1-hydroxy-5-[(1R,3R,4S,5S)-4-hydroxy-1,3,5-trimethyl-6-oxooctyl]-6,8,16,18-tetramethyl-, (1R,5S,6R,8R,9E,11R,15E,17R)-
- CAS:
- 33538-71-5
- MF:
- C41H67NO11
- MW:
- 749.97
- EINECS:
- 251-568-3
- Product Categories:
-
- Antibiotic
- Mol File:
- 33538-71-5.mol
VENTURICIDIN A Chemical Properties
- Melting point:
- 145-147°; mp 140-142°
- alpha
- D +119° (c = 0.5 in chloroform)
- Boiling point:
- 874.9±65.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- pka
- 11.80±0.70(Predicted)
- form
- White to off-white solid.
VENTURICIDIN A Usage And Synthesis
Description
Venturicidin A is a macrolide antibiotic isolated from strains of Streptomyces. It is active against fungi in the genus Venturia which cause apple scab, as well as other fungi, but not against higher plants. Venturicidin A is also cytotoxic against trypanosomes (IC50 = 120-
Uses
The macrolide antibiotic, Venturicidin A, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Venturicidin A was originally isolated as an antifungal agent.
Uses
Venturicidin A is an antibiotic and potent inhibitor of mitochondrial ATP synthase.
Definition
ChEBI: Venturicidin a is a diterpene lactone.
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VENTURICIDIN A(33538-71-5)Related Product Information
- Venturicidin
- Methyl (S)-(+)-3-hydroxybutyrate
- Isobutyl butyrate
- 1,4-Pentadien-3-ol
- 2-METHYL-1-PENTEN-3-OL
- TRANS-5-DECEN-1-OL
- n-Butyl carbamate
- 4-METHYL-4-HEPTEN-3-OL
- 2-HEXEN-4-OL
- (+)-METHYL (S)-3-HYDROXYPENTANOATE
- N-PROPYLCARBAMATE
- 2-OCTEN-4-OL
- Ethyl (S)-3-hydroxybutyrate
- Methyl (R)-(-)-3-hydroxybutyrate
- TRANS-2-DODECEN-1-OL
- 2-HEPTEN-4-OL
- TRANS-2-UNDECEN-1-OL
- 2-(ALLYLOXY)TETRAHYDROPYRAN