Dimesna Chemical Properties

Melting point:

273 °C (decomp)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

EPA Substance Registry System

Ethanesulfonic acid, 2,2'-dithiobis-, disodium salt (16208-51-8)

Safety Information

HS Code 

2930909899

Dimesna Usage And Synthesis

Chemical Properties

White Solid

Uses

Dimesna (Mesna EP Impurity D) reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.

Uses

Dimesna reacts with acrolein and other urotoxic metabolites of oxazaphosphorines (cyclophosphamide or ifosfamide) to form stable, non-urotoxic compounds. Mesna does not have any antitumour activity, nor does it appear to interfere with the antitumour activity of antineoplastic drugs. This medication is used to protect the bladder wall from the harmful effects of some cancer-fighting drugs.

Dimesna(16208-51-8)Related Product Information

• Mesna
• Sodium 1-heptanesulfonate
• (+/-)-10-CAMPHORSULFONIC ACID SODIUM SALT
• Ethanesulfonic acid
• Sodium 3-nitrobenzenesulphonate
• Sodium diphenylamine-4-sulfonate
• Sodium isethionate
• MES monohydrate
• Sodium allylsulfonate
• 1-DODECANESULFONIC ACID SODIUM SALT
• Sodium lignosulfonate
• 4-Morpholineethanesulfonic acid
• Thiamine disulfide
• Ethylenediaminetetraacetic acid disodium salt
• Sodium xylenesulfonate
• Antirust agent T702
• Diallyldisulfide
• Dimethyl disulfide