(RS)-AMPA Chemical Properties

Melting point:

240-252 °C

Boiling point:

320.64°C (rough estimate)

Density 

1.3962 (rough estimate)

refractive index 

1.4880 (estimate)

storage temp. 

0-6°C

solubility 

H₂O: 1 mg/mL warm

form 

solid

color 

white

Water Solubility 

Soluble in warm water at 1mg/ml. Also soluble in 0.1M NaOH or 0.1M HCl at approximately 4mg/ml. Soluble in DMSO at 4mg/ml

Stability:

Store in freezer at -20°C

CAS DataBase Reference

74341-63-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Safety Statements 

24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

(RS)-AMPA Usage And Synthesis

Chemical Properties

White-to-Off White Powder

Uses

A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.

Uses

Selective quisqualate agonist

Definition

ChEBI: (S)-AMPA is a non-proteinogenic alpha-amino acid.

Biological Activity

Prototypical and defining agonist for the AMPA subgroup of ionotropic glutamate receptors.

(RS)-AMPA(74341-63-2)Related Product Information

• (RS)-AMPA
• (S)-AMPA
• (R,S)-2-AMINO-3-[3-(CARBOXYMETHOXY)-5-METHYL-ISOXAZOL-4-YL]-PROPIONIC ACID, SESQUIHYDRATE
• ETHYL 2-ACETAMIDO-2-ETHOXYCARBONYL-3-[3-(ETHOXYCARBONYLMETHOXY)-5-METHYLISOXAZOL-4-YL]PROPANOATE
• (S)-ATPA
• AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPIONIC ACID, DL-ALPHA-[5-METHYL-3H]
• (R)-ATPA
• ATPA
• (RS)-AMPA HYDROBROMIDE
• (R,S)-2-AMINO-3-[5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL]PROPIONIC ACID
• AMINO-3-HYDROXY-5-METHYLISOXAZOLE-4-PROPRIONIC ACID, S-ALPHA-[5-METHYL-3H]-
• (R)-AMPA
• ETHYL 2-ACETAMIDO-2-ETHOXYCARBONYL-3-[3-HYDROXY-5-METHYLISOXAZOL-4-YL]PROPANOATE
• (+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-ISOXAZOLE-4-PROPIONIC ACID DIHYDRATE
• AMOA
• (RS)-AMPA