(RS)-AMPA Chemical Properties

Melting point:

240 °C

Density 

1.386±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

H₂O: 1.2 mg/mL

pka

2.15±0.10(Predicted)

form 

solid

color 

white

Water Solubility 

Soluble in water (10mM, gentle warming)

Stability:

Hygroscopic

CAS DataBase Reference

77521-29-0

EPA Substance Registry System

.alpha.-Amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (77521-29-0)

Safety Information

WGK Germany 

3

HS Code 

2934999090

MSDS

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(RS)-AMPA Usage And Synthesis

Chemical Properties

White-to-Off White Powder

Uses

A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists

Uses

AMPA is the defining agonist for the AMPA subgroup of ionotropic glutamate receptors, which mediate excitatory neurotransmission. Because AMPA does not interfere with binding sites for kainic acid or NMDA , it can be used to distinguish AMPA receptor-specific activity that contributes to a neuronal response. (R,S)-AMPA contains an equal mixture of the active (S)-enantiomer and the inactive (R)-enantiomer.

Definition

ChEBI: (S)-AMPA is a non-proteinogenic alpha-amino acid.

Biological Activity

More water soluble hydrobromide salt of ( RS )-AMPA ((RS)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionicacid ).

storage

Room temperature

(RS)-AMPA(77521-29-0)Related Product Information

• CYCLOTHIAZIDE
• NBQX DISODIUM SALT
• KYNURENIC ACID
• 1-(4'-AMINOPHENYL)-3,5-DIHYDRO-7,8-DIMETHOXY-4H-2,3-BENZODIAZEPIN-4-ONE
• DNQX
• CNQX
• (S)-AMPA
• (RS)-AMPA
• (RS)-AMPA HYDROBROMIDE