E3 ligase Ligand-Linker Conjugates 37
E3 ligase Ligand-Linker Conjugates 37 Basic information
- Product Name:
- E3 ligase Ligand-Linker Conjugates 37
- Synonyms:
-
- cIAP1 Ligand-Linker Conjugates 2
- E3 ligase Ligand-Linker Conjugates 37
- 12,15-Dioxa-2,6,9-triazaheptadecanoic acid, 17-amino-4-hydroxy-7-(2-methylpropyl)-5,8-dioxo-3-(phenylmethyl)-, 9H-fluoren-9-ylmethyl ester, (3R,4S,7S)-
- CAS:
- 1312302-14-9
- MF:
- C37H48N4O7
- MW:
- 660.8
- Mol File:
- 1312302-14-9.mol
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E3 ligase Ligand-Linker Conjugates 37 Chemical Properties
- Boiling point:
- 921.3±65.0 °C(Predicted)
- Density
- 1.200±0.06 g/cm3(Predicted)
- pka
- 11.15±0.46(Predicted)
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E3 ligase Ligand-Linker Conjugates 37 Usage And Synthesis
Uses
cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs[1].
IC 50
cIAP1
References
[1] Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78. DOI:10.1016/j.bmc.2011.09.041
E3 ligase Ligand-Linker Conjugates 37Supplier
Jilin Province Woda Biotechnology Co., Ltd.
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TargetMol Chemicals Inc.
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TargetMol Chemicals Inc.
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Henan Mengtai Pharmaceutical Technology Co., Ltd
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E3 ligase Ligand-Linker Conjugates 37(1312302-14-9)Related Product Information
- E3 ligase Ligand 12
- Acetic acid, 2-[2-[2-[2-[3-[[2-[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-1-oxopropyl]amino]acetyl]-2-pyrrolidinyl]-4-thiazolyl]carbonyl]phenoxy]ethoxy]ethoxy]ethoxy]-
- E3 ligase Ligand-Linker Conjugates 41
- E3 ligase Ligand-Linker Conjugates 33
- E3 ligase Ligand 11
- E3 ligase Ligand-Linker Conjugates 36
- E3 ligase Ligand-Linker Conjugates 39
- E3 ligase Ligand-Linker Conjugates 34
- E3 ligase Ligand-Linker Conjugates 38