(R)-(-)-2-Amino-1-propanol Chemical Properties

Melting point:

8 °C

Boiling point:

173-176 °C(lit.)

alpha 

-17 º (c=neat)

Density 

0.965

refractive index 

n20/D 1.450(lit.)

Flash point:

183 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

pka

12.88±0.10(Predicted)

form 

Oily Liquid

color 

Clear colorless to light yellow

Specific Gravity

0.965

optical activity

[α]19/D 18°, neat

Water Solubility 

SOLUBLE

Sensitive 

Hygroscopic

BRN 

1718866

CAS DataBase Reference

35320-23-1(CAS DataBase Reference)

NIST Chemistry Reference

(R)-(-)-2-Amino-1-propanol(35320-23-1)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

34-36/37/38

Safety Statements 

26-36/37/39-45-36

RIDADR 

UN 2735 8/PG 2

WGK Germany 

3

F 

10-23

Hazard Note 

Corrosive/Hygroscopic

HazardClass 

8

PackingGroup 

III

HS Code 

29221990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

(R)-(-)-2-Amino-1-propanol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-2-Amino-1-propanol has been used as a derivatizing agent for gossypol during the analysis of gossypol enantiomers in cottonseed by high-performance liquid chromatography.

Application

R)-(-)-2-Amino-1-propanol is used as a chiral intermediate for the synthesis of pharmaceutical products and agrochemicals. It acts as additives in health care products and animal feed. It is a amino alcohol obtained by reduction of d-alanine. This compound could be converted into the corresponding nonracemic adenine derivative (R)-9-(1-Methyl-2-hydroxyethyl)adenine through minor variations on the classic Montgomery sequence[1].

General Description

(R)-(-)-2-Amino-1-propanol is a chiral secondary amine.

References

[1] Jeffery A, et al. Synthesis of Acyclic Nucleoside and Nucleotide Analogues from Amino Acids: A Convenient Approach to a PMEA±PMPA Hybrid. Tetrahedron, 2000; 56: 5077-5083.

(R)-(-)-2-Amino-1-propanol(35320-23-1)Related Product Information

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