valnoctamide
valnoctamide Basic information
- Product Name:
- valnoctamide
- Synonyms:
-
- valnoctamide
- 2-Ethyl-3-methylpentan-amide
- 2-Ethyl-3-methylvaleramide
- Axiquel
- McN-X-181
- Nirvani
- Valmethamide
- Nirvanil
- CAS:
- 4171-13-5
- MF:
- C8H17NO
- MW:
- 143.23
- EINECS:
- 224-033-7
- Product Categories:
-
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 4171-13-5.mol
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valnoctamide Chemical Properties
- Melting point:
- 113.5-1140C
- Boiling point:
- 261.35°C (rough estimate)
- Density
- 0.9636 (rough estimate)
- refractive index
- 1.4614 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- pka
- 16.81±0.50(Predicted)
- color
- white to off-white
- Water Solubility
- 8.70g/L(temperature not stated)
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valnoctamide Usage And Synthesis
Description
Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
Chemical Properties
Crystalline Solid
Uses
Isomer of Valpromide. Anxiolytic.
Definition
ChEBI: Valnoctamide is a fatty amide.
brand name
Axiquel (Ortho-McNeil).
valnoctamideSupplier
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
Chemsky(shanghai)International Co.,Ltd.
- Tel
- 021-50135380
- shchemsky@sina.com
Shanghai Hongye Biotechnology Co. Ltd
- Tel
- 400-9205774
- sales@glpbio.cn
Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
Fan De(Beijing) Biotechnology Co., Ltd.
- Tel
- 15911056312
- liming@bio-fount.com
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valnoctamide(4171-13-5)Related Product Information
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- 2-[(2-CARBOXY-CYCLOHEXANECARBONYL)-AMINO]-BENZOIC ACID METHYL ESTER
- Cytochalasin H
- CYTOCHALASIN A
- CYTOCHALASIN E
- AKOS BBS-00007887
- 2-(3,4-DICHLORO-PHENYLCARBAMOYL)-CYCLOHEXANECARBOXYLIC ACID
- DIHYDROCYTOCHALASIN B
- BISPYRAZOLONE