valnoctamide
- Product Name
- valnoctamide
- CAS No.
- 4171-13-5
- Chemical Name
- valnoctamide
- Synonyms
- Axiquel;Nirvani;Nirvanil;McN-X-181;NSC-32363;valnoctamide;Valmethamide;2-Ethyl-3-methylvaleramide;2-Ethyl-3-methylpentan-amide;Pentanamide, 2-ethyl-3-methyl-
- CBNumber
- CB7931541
- Molecular Formula
- C8H17NO
- Formula Weight
- 143.23
- MOL File
- 4171-13-5.mol
valnoctamide Property
- Melting point:
- 113.5-1140C
- Boiling point:
- 261.35°C (rough estimate)
- Density
- 0.9636 (rough estimate)
- refractive index
- 1.4614 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- pka
- 16.81±0.50(Predicted)
- color
- white to off-white
- Water Solubility
- 8.70g/L(temperature not stated)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- V4765
- Product name
- Valnoctamide
- Purity
- ≥98% (NMR)
- Packaging
- 5mg
- Price
- $71.62
- Updated
- 2025/07/31
- Product number
- V4765
- Product name
- Valnoctamide
- Purity
- ≥98% (NMR)
- Packaging
- 25mg
- Price
- $298
- Updated
- 2025/07/31
- Product number
- 18456
- Product name
- Valnoctamide
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 18456
- Product name
- Valnoctamide
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- 18456
- Product name
- Valnoctamide
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $93
- Updated
- 2024/03/01
valnoctamide Chemical Properties,Usage,Production
Description
Valnoctamide is an isomer of the valproic acid amide, valpromide. It has been marketed as an anxiolytic and sedative compound and suppresses neuropathic pain. Unlike valpromide, valnoctamide is not metabolized to its acid form, valnoctic acid, in vivo and has no teratogenicity. It abolishes the activity of myo-inositol-1-phosphate synthase in human brain crude homogenates (Ki = 0.18 mM). Valnoctamide suppresses electrographic seizures in animal models of status epilepticus, suggesting potential applications in managing epilepsy.
Chemical Properties
Crystalline Solid
Uses
Isomer of Valpromide. Anxiolytic.
Definition
ChEBI: Valnoctamide is a fatty amide.
brand name
Axiquel (Ortho-McNeil).
References
[1] ROGAWSKI M A. Diverse mechanisms of antiepileptic drugs in the development pipeline[J]. Epilepsy Research, 2006, 69 3: Pages 273-294. DOI: 10.1016/j.eplepsyres.2006.02.004
[2] ILAN WINKLER. Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain[J]. British Journal of Pharmacology, 2009, 146 2: 198-208. DOI: 10.1038/sj.bjp.0706310
[3] GALIT SHALTIEL. Effect of valproate derivatives on human brain myo-inositol-1-phosphate (MIP) synthase activity and amphetamine-induced rearing.[J]. Pharmacological Reports, 2007, 59 4: 402-407.
[4] JAY SPAMPANATO F. E D. Valnoctamide enhances phasic inhibition: A potential target mechanism for the treatment of benzodiazepine-refractory status epilepticus[J]. Epilepsia, 2014, 55 9: e94-e98. DOI: 10.1111/epi.12702
valnoctamide Preparation Products And Raw materials
Raw materials
Preparation Products
valnoctamide Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
- 32321
- Advantage
- 50
- Tel
- 400-9205774
- sales@glpbio.cn
- Country
- China
- ProdList
- 6777
- Advantage
- 58
- Tel
- +86-400-002-6226 +86-13028896684;
- sales@rrkchem.com
- Country
- China
- ProdList
- 57422
- Advantage
- 58
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9729
- Advantage
- 58
- Tel
- 025-58859352 13155353615
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15525
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 13348960310
- 3003867561@qq.com
- Country
- China
- ProdList
- 10503
- Advantage
- 58
View Lastest Price from valnoctamide manufacturers
- Product
- valnoctamide 4171-13-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-26