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Cryptochlorogenic acid

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Cryptochlorogenic acid Basic information

Product Name:
Cryptochlorogenic acid
Synonyms:
  • Cryptochlorogenic acid
  • 3,4-Dihydroxycinnamic acid 4-carboxy-2,4,6-trihydroxycyclohexyl ester
  • 4-Caffeoylquinic acid
  • Quinic acid 4-O-caffeate
  • Cryptochlorogenic acid,4-Caffeoylquinic acid
  • 4-Dicaffeoylquinic Acid
  • 4-Caffeoylquinic acid Quinic acid 4-O-caffeate
  • Cryptochlorogenic acid(4')
CAS:
905-99-7
MF:
C16H18O9
MW:
354.31
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
905-99-7.mol
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Cryptochlorogenic acid Chemical Properties

Boiling point:
694.9±55.0 °C(Predicted)
Density 
1.65
storage temp. 
2-8°C
solubility 
DMSO : 50 mg/mL (141.12 mM; Need ultrasonic)
pka
4.07±0.50(Predicted)
color 
White-pale yellow
optical activity
[α]/D -76.0±5.0°, c = 0.5 in H2O
Stability:
Hygroscopic
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Safety Information

WGK Germany 
3
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Cryptochlorogenic acid Usage And Synthesis

Uses

Cryptochlorogenic acid may be used as a reference standard in the determination of cryptochlorogenic acid in the leaves of Hibiscus sabdariffa using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).

Uses

4-O-Caffeoylquinic acid has been used as a reference compound for the quantification in high performance liquid chromatography-diode array detector (HPLC-DAD).

Definition

ChEBI: A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 4-hydroxy group of (+)-quinic acid.

General Description

Cryptochlorogenic acid is a polyphenol, found in a variety of plants, which plays a crucial role in protection against various age-related diseases.

Biochem/physiol Actions

4-O-Caffeoylquinic acid (4-CQA) is a major active antioxidant marker in mulberry leaf extract. It is an inhibitor of ferroptosis hence, it is recognized as a potent anti-diabetic agent. 4-CQA plays an important role in the upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway.

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