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ChemicalBook >  Product Catalog >  Biochemical Engineering >  Amino Acids and Derivatives >  Valine derivatives >  N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID

N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID

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N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Basic information

Product Name:
N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID
Synonyms:
  • L-Threonine,N-[(1,1-diMethylethoxy)carbonyl]-3-Methyl-
  • EOS-60980
  • 3-Hydroxy-L-valine, N-BOC protected
  • N-(tert-Butoxycarbonyl)-3-hydroxy-L-valine, (2S)-2-Amino-3-hydroxy-3-methylbutanoic acid, N-BOC protected
  • N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine
  • (S)-N-ALPHA-T-BUTYLOXYCARBONYL-3,3-DIMETHYL-SERINE
  • (S)-2-BOC-AMINO-3-HYDROXY-3-METHYLBUTYRIC ACID
  • N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID
CAS:
102507-13-1
MF:
C10H19NO5
MW:
233.26
Product Categories:
  • unnatural amino acids
  • pharmacetical
Mol File:
102507-13-1.mol
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N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Chemical Properties

Melting point:
116-118℃
Boiling point:
391.1±37.0 °C(Predicted)
Density 
1.175±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
3.62±0.10(Predicted)
color 
White to Off-White
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
29225090
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N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID Usage And Synthesis

Chemical Properties

White powder

Uses

N-Boc-3-hydroxy-L-valine is used as a reagent in the synthesis of metabolites of PPI-2458, which is a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). N-Boc-3-hydroxy-L-valine is also used in the preparation of Boceprevir (B674500); an NS3 serine protease inhibitor of hepatitis C virus for the treatment of HCV infection.

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