REVEROMYCIN D
REVEROMYCIN D Basic information
- Product Name:
- REVEROMYCIN D
- Synonyms:
-
- REVEROMYCIN D
- Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-3-pentyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
- CAS:
- 144860-70-8
- MF:
- C37H54O11
- MW:
- 674.82
- Mol File:
- 144860-70-8.mol
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REVEROMYCIN D Chemical Properties
- Boiling point:
- 855.3±65.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- White to tan solid.
- pka
- 4.36±0.17(Predicted)
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REVEROMYCIN D Usage And Synthesis
Description
Reveromycin D is a bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells and has pH-dependent antifungal activity against C. albicans (MICs = 2 and >500 μg/ml at pH 3 and 7.4, respectively). Reveromycin D also inhibits proliferation of KB and K562 cells (IC50s = 1.6 and 1.3 μg/ml, respectively).
Uses
Reveromycin D is the isopentyl analogue and a minor component of the reveromycin complex, isolated from a Streptomyces sp.. Published information on reveromycin D suggests that it is more active than its straight chain analogue, reveromycin C.
Uses
Reveromycin D is a minor component of the reveromycin complex.
REVEROMYCIN DSupplier
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