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Lancovutide

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Lancovutide Basic information

Product Name:
Lancovutide
Synonyms:
  • 2-l-lysine-6-(3-aminoalanine)-10-l-phenylalanine-12-l-phenylalanine-ancoveni
  • antibioticpa48009
  • cyclic6-19)-imine
  • leucopeptin
  • DURAMYCIN
  • duramycin from streptoverticillium*cinnamoneus
  • lancovutide
  • duramycin from streptoverticillium*ci·Namoneus
CAS:
1391-36-2
MF:
C89H125N23O25S3
MW:
2013.28
Product Categories:
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Chemical Structure Class
  • Interferes with Protein SynthesisAntibiotics
  • Mechanism of Action
  • Spectrum of Activity
  • Tetracyclines
Mol File:
1391-36-2.mol
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Lancovutide Chemical Properties

Melting point:
271-273 ºC
Density 
1.0238 (rough estimate)
refractive index 
1.6680 (estimate)
storage temp. 
2-8°C
solubility 
0.1 M HCl: soluble10mg/mL
form 
powder
pka
3.15±0.11(Predicted)
color 
Off-White to Pale Yellow
Sequence
Cys-Lys-Gln-Cys-Cys-Ala-Phe-Gly-Pro-Phe-{Abu}-Phe-Val-Cys-Asp-Gly-Asn-{Abu}-Lys-NH2 (Disulfide bridge: Cys1-Abu18, Cys4-Cys14, Cys5-Abu11)
Stability:
Hygroscopic
InChIKey
BPIFGBWRBGTMHX-OHSSMEBINA-N
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Safety Information

WGK Germany 
3
RTECS 
BV7100000
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Lancovutide Usage And Synthesis

Uses

Duramycin is a chloride secretion enhancer in airway epithelium.

in vivo

Evaluation of [68Ga]NODAGA-Duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity. Organ uptake is analyzed in untreated and doxorubicin, busulfan, and cisplatin-treated mice 2 h after intravenous injection of [68Ga]NODAGA-Duramycin. [68Ga]NODAGA-Duramycin PET/CT is successfully applied to non-invasively detect chemotherapy-induced organ toxicity with high sensitivity in mice[3].

LancovutideSupplier

Zhejiang Huida Biotech Co., LTD Gold
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0571-89903882 18679456698
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mingxinzhu@huidabiotech.com
Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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Alfa Chemistry
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Creative Peptides
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