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COPPER(II) TRIFLUOROMETHANESULFONATE

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COPPER(II) TRIFLUOROMETHANESULFONATE Basic information

Product Name:
COPPER(II) TRIFLUOROMETHANESULFONATE
Synonyms:
  • Copper (Ii) Trifluorome
  • Copper(II) trifluoromethanesulfonate,Copper(II) triflate, Cupric trifluoromethanesulfonate, Trifluoromethanesulfonic acid copper(II) salt
  • Copper(II) trifluoromethanesulfonate 98%
  • Trifluoromethanesulfonic acid copper(II)
  • Copper(Ⅱ) trifluoroMethanesulfonate
  • Cupric trifluoroMethylsulfonate
  • Copper(II) trifluoroMethanesulfonate,98% Cu(CF3SO3)2
  • Copper(II) Triflate Trifluoromethanesulfonic Acid Copper(II) Salt
CAS:
34946-82-2
MF:
C2CuF6O6S2
MW:
361.68
EINECS:
252-300-8
Product Categories:
  • Biochemistry
  • Catalysts for Organic Synthesis
  • Classes of Metal Compounds
  • Cu (Copper) Compounds
  • Homogeneous Catalysts
  • Metal Triflates
  • Reagents for Oligosaccharide Synthesis
  • Synthetic Organic Chemistry
  • Transition Metal Compounds
  • metal triflate compounds
  • triflate
  • Cu
  • OTf&NTf series
Mol File:
34946-82-2.mol
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COPPER(II) TRIFLUOROMETHANESULFONATE Chemical Properties

Melting point:
≥300 °C
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Water (Slightly)
form 
Powder
color 
White to slightly blue or light gray
Water Solubility 
Soluble in water.
Sensitive 
Hygroscopic
Hydrolytic Sensitivity
6: forms irreversible hydrate
BRN 
4028198
Exposure limits
ACGIH: TWA 1 mg/m3
NIOSH: IDLH 100 mg/m3; TWA 1 mg/m3
Stability:
hygroscopic
InChIKey
SBTSVTLGWRLWOD-UHFFFAOYSA-L
CAS DataBase Reference
34946-82-2(CAS DataBase Reference)
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Safety Information

Hazard Codes 
C,Xi
Risk Statements 
34
Safety Statements 
26-36/37/39-45-27
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
3-10
Hazard Note 
Irritant/Hygroscopic
TSCA 
No
HazardClass 
8
PackingGroup 
III
HS Code 
29049085

MSDS

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COPPER(II) TRIFLUOROMETHANESULFONATE Usage And Synthesis

Reaction

  1. Ring-Opening of epoxides and aziridines.
  2. Asymmetric conjugate addition of organozinc reagents to α,β-unsaturated ketones.
  3. Electrophilic addition of olefins.
  4. Asymmetric aziridination of olefins.
  5. Asymmetric cycloadditions and aldol condensations.
  6. Asymmetric Kharasch oxidation.
  7. Asymmetric Michael addition of enamides.
  8. Asymmetric O-H or O-R insertion reactions.
  9. Enantioselective intramolecular aminooxygenation of alkenes.
  10. Enantioselective addition of dialkylzinc reagents to N-acylpyridinium salts.
  11. Pd-catalyzed C-H functionalizations of oximes with arylboronic acids.
  12. Used as a Lewis acid in the Nazarov cyclization.
  13. Catalyst in the diacetoxylation olefins.
  14. Catalyst in the meta-selective direct arylation of α-aryl carbonyl compounds.
  15. Catalyst in the three-component coupling of amines, aldehydes, and alkynes.


Chemical Properties

white to slightly blue or light grey cryst. powder

Uses

Copper(II) trifluoromethanesulfonate is a mild lewis acid. It is used as catalyst which promotes dehydration of alcohols and diols to alkenes at ambient temperatures. It is widely used to generate carbenoid species from ?-diazo esters and ketones, via in situ reduction to the Cu(I) species. It is also promotes the reaction between diazo esters and imines to give aziridines. It catalyzes syn-selective aldol condensation of (Z)-silyl enol ethers with aldehydes, Friedel-Crafts alkylation, acylation reactions of aromatics and addition of trimethylsilyl cyanide to carbonyl compounds.

Purification Methods

Dissolve it in MeCN, add dry Et2O until cloudy and cool at -20o in a freezer. The light blue precipitate is collected and dried in a vacuum oven at 130o/20mm for 8hours. It has 737nm ( 22.4 max M1cm -1) in AcOH. [Salomon & Kochi J Am Chem Soc 95 330 1973]. It has also been dried in a vessel at 0.1Torr by heating with a Fischer burner [Andrist et al. J Org Chem 43 3422 1978]. It has been dried at 110-120o/5mm for 1hour before use and forms a *benzene complex which should be handled in a dry box because it is air sensitive [Kobayashi et al. Chem Pharm Bull Jpn 28 262 1980, Salomon & Kochi J Am Chem Soc 95 330 1973]. [Beilstein 3 IV 34.]

COPPER(II) TRIFLUOROMETHANESULFONATE Preparation Products And Raw materials

Raw materials

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