7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene Chemical Properties

Boiling point:

424.2±38.0 °C(Predicted)

Density 

1.773

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

Appearance

White to off-white Solid

7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene Usage And Synthesis

Synthesis

Synthesis of Intermediate 1: 30.27 g (110.8 mmol) of 9,9-dimethyl-2-bromofluorene, 16.9 g (66.5 mmol) of iodine (I2) and 15.2 g (66.5 mmol) of periodate (H5IO6) were dissolved in acetic acid (AcOH). To this solution, dilute aqueous sulfuric acid (H2SO4) was slowly added dropwise and the reaction was stirred at 50°C for 5 hours. Upon completion of the reaction, deionized water was added to the reaction mixture and a solid precipitate was precipitated. The precipitate was collected by filtration to give 37.6 g of intermediate 1 in 85% yield. The resulting compound was structurally confirmed by high resolution mass spectrometry (HR-MS).

References

[1] Angewandte Chemie - International Edition, 2016, vol. 55, # 44, p. 13724 - 13728
[2] Angew. Chem., 2016, vol. 128, p. 13928 - 13932,5
[3] Patent: EP2292603, 2011, A1. Location in patent: Page/Page column 24
[4] Patent: EP2738166, 2014, A1. Location in patent: Paragraph 0153-0154
[5] Patent: EP2762478, 2014, A1. Location in patent: Paragraph 0179; 0180

7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene(319906-45-1)Related Product Information

• Dacthal
• Dimethyl fumarate
• Dimethyl sulfoxide
• Dimethyl sulfone
• Poly(dimethylsiloxane)
• N,N-Dimethylformamide
• N,N-Dimethylacetamide
• 2-Bromo-9,9-dihexyl fluorene
• Dichlorodimethylsilane
• Dimethyl ether
• N,N-Dimethylaniline
• Fluorene
• Dimethyl carbonate
• Dimethyl sulfate
• ETHANE
• Bromine
• 9,9-Dimethyl-9H-fluorene
• 7-Bromo-2-iodo-9,9-dimethyl-9H-fluorene