Basic information Safety Supplier Related

Monoclonal antibody 6B1 igg4

Basic information Safety Supplier Related

Monoclonal antibody 6B1 igg4 Basic information

Product Name:
Monoclonal antibody 6B1 igg4
Synonyms:
  • Cat-152
  • Human igg-4 anti-tgfb2 monoclonal antibody
  • Human igg4 anti-transforming growth factor-beta 2 monoclonal antibody
  • Lerdelimumab
  • Lerdelimumab [inn]
  • Monoclonal antibody 6B1 igg4
  • Research Grade Lerdelimumab
CAS:
285985-06-0
MW:
0
Mol File:
Mol File
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Monoclonal antibody 6B1 igg4 Usage And Synthesis

Uses

Lerdelimumab (CAT-152) is an IgG4 human anti-TGF-β2 recombinant monoclonal antibody. Lerdelimumab can be used as an anti-scarring agent for glaucoma research[1][2].

in vivo

Lerdelimumab (100 μL, 1 mg/mL; subconjunctival injection; on days 2, 3, 4, 7, 9, 11 and 14 after surgery) significantly improves glaucoma surgical outcome and reduces the risk of corneal side effects[1].

References

[1] Mead AL, et al. Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery. Invest Ophthalmol Vis Sci. 2003 Aug;44(8):3394-401. DOI:10.1167/iovs.02-0978
[2] Wormstone IM, et al. TGF-beta2-induced matrix modification and cell transdifferentiation in the human lens capsular bag. Invest Ophthalmol Vis Sci. PMID:12091431

Monoclonal antibody 6B1 igg4Supplier

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