Basic information Safety Supplier Related

SB 242084 (hydrochloride)

Basic information Safety Supplier Related

SB 242084 (hydrochloride) Basic information

Product Name:
SB 242084 (hydrochloride)
Synonyms:
  • SB 242084 (hydrochloride)
  • SB-242084 HCl salt
  • CAS 1049747-87-6
  • SB242084;SB 242084;CAS 1049747-87-6
  • SB 242084 2HCL
CAS:
1049747-87-6
MF:
C21H21Cl3N4O2
MW:
467.77604
Product Categories:
  • API
Mol File:
1049747-87-6.mol
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SB 242084 (hydrochloride) Chemical Properties

storage temp. 
Sealed in dry,Room Temperature
solubility 
Ethanol:1.0(Max Conc. mg/mL);2.14(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);21.38(Max Conc. mM)
DMSO:59.63(Max Conc. mg/mL);127.47(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);64.13(Max Conc. mM)
form 
A crystalline solid
color 
Off-white to light yellow
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SB 242084 (hydrochloride) Usage And Synthesis

Description

Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that activates specific receptors located primarily in the gut and central nervous system. SB-242084 is an antagonist of the 5-HT2C receptor (pKi = 9.0), with at least 100-fold more selectivity over other 5-HT, dopamine, or adrenergic receptors. In vivo, it is brain penetrant and has significant anxiolytic activity, without sedative, proconvulsant, or hyperphagic properties. SB-242084 has been used extensively in animal research to evaluate, for example, 5-HT2C receptor agonists and neurotransmitter receptor interactions in mice.

Uses

SB 242084 Hydrochloride is an antagonist of the SR-2C.

Definition

ChEBI: 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide;dihydrochloride is an organic molecular entity, an indole alkaloid and a pyridine. It has a role as a receptor modulator.

storage

Desiccate at +4°C

SB 242084 (hydrochloride)Supplier

Shanghai Aladdin Bio-Chem Technology Co.,LTD
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400-400-6206333 18521732826
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market@aladdin-e.com
MedChemexpress LLC
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021-58955995
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sales@medchemexpress.cn
ShangHai Biochempartner Co.,Ltd
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177-54423994 17754423994
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2853530910@QQ.com
Amadis Chemical Company Limited
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571-89925085
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sales@amadischem.com
Musechem
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+1-800-259-7612
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info@musechem.com