SB 269970 HYDROCHLORIDE CAS#: 201038-74-6

SB 269970 HYDROCHLORIDE Basic information

Product Name:

SB 269970 HYDROCHLORIDE

Synonyms:

CS-776
SB-269970;SB 269970
SB 269970 HYDROCHLORIDE
SB269970HCl
(2R)-1-[(3-HYDROXYPHENYL)SULFONYL]-2-[2-(4-METHYL-1-PIPERIDINYL)ETHYL]PYRROLIDINE HYDROCHLORIDE
Pyrrolidine, 1-((3-hydroxyphenyl)sulfonyl)-2-(2-(4-methyl-1-piperidinyl)ethyl)-, (R)-
(R)-1-[(3-Hydroxyphenyl)sulfonyl]-2-[2-(4-methyl-1-piperidinyl)ethyl]pyrrolidine
(R)-3-((2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidin-1-yl)sulfonyl)phenol

CAS:

201038-74-6

MF:

C18H28N2O3S

MW:

352.49

Product Categories:

Serotonin receptor

Mol File:

201038-74-6.mol

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SB 269970 HYDROCHLORIDE Chemical Properties

Boiling point:: 512.9±56.0 °C(Predicted)
Density: 1.188
storage temp.: Inert atmosphere,2-8°C
solubility: H₂O: 22 mg/mL
form: solid
pka: 8.88±0.10(Predicted)

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Safety Information

WGK Germany: 3

MSDS

Language:English Provider:SigmaAldrich

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SB 269970 HYDROCHLORIDE Usage And Synthesis

Uses

SB 269970 is a selective and potent SR-7 antagonist.

Definition

ChEBI: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol is a sulfonamide.

Biological Activity

Potent and selective 5-HT 7 receptor antagonist (pK i values are 8.9, 7.2 and 6.0 for 5-HT 7A , 5-HT 5A and 5-HT 1B and < 6.0 for 5-HT 1A , 5-HT 1D , 5-HT 1E , 5-HT 1F , 5-HT 2A , 5-HT 2B , 5-HT 2C , 5-HT 4 and 5-HT 6 receptors respectively). Brain penetrant in vivo .

SB 269970 HYDROCHLORIDESupplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com

Chengdu NoVi Biotechnology Co., Ltd.

Tel: 028-81458053
Email: novibiotech@163.com sales@novi-biotech.com

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Email: info@adooq.com

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Email: info@adooq.cn

SPIRO PHARMA

Tel
Email: eric_feng1954@126.com

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