Basic information Safety Supplier Related

DihydroarteMisinic acid

Basic information Safety Supplier Related

DihydroarteMisinic acid Basic information

Product Name:
DihydroarteMisinic acid
Synonyms:
  • DihydroarteMisinic acid
  • (alphaR,1R,4R,4aS,8aS)-1,2,3,4,4a,5,6,8a-Octahydro-alpha,4,7-trimethyl-1-naphthaleneacetic acid
  • Dihydroarteannuic acid
  • (2R)-dihydroartemisinic acid
  • 2-(4,7-dimethyl-(1α-H),2,3,(4β-H),(4aα-H),5,6,(8aα-H)-octahydronaphthalen-1-yl)propionic acid
  • Dihydroqinghao acid
  • Dihydro-Artmisinic Acid
  • product/154911
CAS:
85031-59-0
MF:
C15H24O2
MW:
236.35
EINECS:
813-723-9
Mol File:
85031-59-0.mol
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DihydroarteMisinic acid Chemical Properties

Melting point:
135-137°C
Boiling point:
358.8±11.0 °C(Predicted)
Density 
0.999±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
4.65±0.10(Predicted)
form 
Solid
color 
White to Off-White
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DihydroarteMisinic acid Usage And Synthesis

Uses

Dihydroartemisinic Acid is produced and its content is increased in Artemisia annua when NAC transcription factor gene (AaNAC1) is overexpressed, which play an important role in response to various abiotic stresses. Also, it is related secondary metabolites of artemisinin which increases in A. annua under cold stress.

Definition

ChEBI: Dihydroartemisinic acid is a monocarboxylic acid that is propanoic acid substituted at position 2 by a (1S,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group. It is a sesquiterpenoid precursor of the antimalarial drug, artemisinin. It has a role as a plant metabolite. It is a carbobicyclic compound, a monocarboxylic acid, a member of octahydronaphthalenes and a sesquiterpenoid. It is a conjugate acid of a dihydroartemisinate.

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