1,2-Difluorobenzene Chemical Properties

Melting point:

−34 °C(lit.)

Boiling point:

92 °C(lit.)

Density 

1.158 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.443(lit.)

Flash point:

36 °F

storage temp. 

Flammables area

solubility 

Chloroform, Methanol

form 

Liquid

Specific Gravity

1.158

color 

Clear colorless

Water Solubility 

Not miscible or difficult to mix in water.

BRN 

1905113

Dielectric constant

14.26

Stability:

Stable. Incompatible with strong oxidizing agents. Highly flammable. Note low flash point.

CAS DataBase Reference

367-11-3(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1,2-difluoro-(367-11-3)

EPA Substance Registry System

Benzene, 1,2-difluoro- (367-11-3)

Safety Information

Hazard Codes 

F,Xn

Risk Statements 

11-20-2017/11/20

Safety Statements 

7-16-29-33-7/9

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

RTECS 

CZ5655000

Hazard Note 

Flammable

HazardClass 

3

PackingGroup 

II

HS Code 

29036990

MSDS

• Language:English Provider:1,2-Difluorobenzene
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

1,2-Difluorobenzene Usage And Synthesis

Chemical Properties

colourless liquid

Uses

1,2-Difluorobenzene is used in electrochemical analysis of transition metal complexes. 1,2-difluorobenzene is also a potent inhibitor of NMDA receptor.

Uses

1,2-Difluorobenzene(1,2-DFB) has been used to study the mechanism of dissociation of o-, m- and p-difluorobenzene ions by threshold photoelectron photoion coincidence spectroscopy. It has been used to study the room temperature adsorption of 1,2-DFB, 1,2-dichlorobenzene and 1,2-dibromobenzene on Si(100)2x1 by X-ray photoelectron spectroscopy and temperature programmed desorption. It is used as solvent in electrochemical studies on transition metal complexes. It is also applied as a solvent useful for electrochemical studies on transition metal complexes.

Definition

ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 2.

General Description

1,2-Difluorobenzene undergoes defluorination under very mild conditions by H₂ in the presence of NaOAc over rhodium pyridylphosphine and bipyridyl complexes tethered on a silica-supported palladium catalyst.

1,2-Difluorobenzene(367-11-3)Related Product Information

• Transfluthrin
• 4-Fluorobenzaldehyde
• Florfenicol
• Ticagrelor Sulfone
• 2-(((3aR,4S,6R,6aS)-6-(7-aMino-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-diMethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
• (3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-difluorophenyl)cyclopropyl)aMino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyriMidin-3-yl)-2,2-
• Ticagrelor Related Compound 3
• TRANSAMINE
• 1,2-Cyclopentanediol, 3-[7-aMino-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyriMidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)-
• 4-Chloro-2-propylsulfanyl-pyrimidine
• Ticagrelor Related Compound 44
• (trans)-2-(3,4-difluorophenyl)cyclopropanecarboxamide
• 4,6-dichloro-2-(propylthio)pyriMidine
• Ticagrelor diastereoMer
• Ticagrelor Impurity N
• Cyclopropanamine, 2-(3-fluorophenyl)-, (1R,2S)- (9CI)
• ethyCyclopropanamine, 2-(3,4-difluorophenyl)-, (1R,2S)- (REACH)
• Triethyl phosphonoacetate