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Ethyl 2-aminothiazole-5-carboxylate

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Ethyl 2-aminothiazole-5-carboxylate Basic information

Product Name:
Ethyl 2-aminothiazole-5-carboxylate
Synonyms:
  • 2-AMINO-THIAZOLE-5-CARBOXYLIC ACID ETHYL ESTER
  • 2-AMINO-THIAZOLE-5-CARBOXYLATE ETHYL ESTER
  • ETHYL 2-AMINOTHIAZOLE-5-CARBOXYLATE
  • ETHYL 2-AMINO-1,3-THIAZOLE-5-CARBOXYLATE
  • BUTTPARK 77\50-04
  • RARECHEM AL BI 1263
  • Thiazole,2-amino-5-carboxylic acid ethyl ester
  • Ethyl-2-aminothiazole-5-carbonylate
CAS:
32955-21-8
MF:
C6H8N2O2S
MW:
172.2
EINECS:
676-105-6
Product Categories:
  • Amines and Anilines
  • Heterocycles
  • Carboxes
  • Thiazoles
  • Thiazole series
  • Thiazole
  • Amines
  • blocks
  • Heterocycle intermediates
Mol File:
32955-21-8.mol
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Ethyl 2-aminothiazole-5-carboxylate Chemical Properties

Melting point:
144-148
Boiling point:
308.0±15.0 °C(Predicted)
Density 
1.336±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Water Solubility 
Insoluble in water
form 
powder to crystal
pka
3.12±0.10(Predicted)
color 
White to Yellow to Orange
Sensitive 
Moisture & Light Sensitive
λmax
299nm(EtOH)(lit.)
InChI
InChI=1S/C6H8N2O2S/c1-2-10-5(9)4-3-8-6(7)11-4/h3H,2H2,1H3,(H2,7,8)
InChIKey
VNZXERIGKZNEKB-UHFFFAOYSA-N
SMILES
S1C(C(OCC)=O)=CN=C1N
CAS DataBase Reference
32955-21-8(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
2
HazardClass 
IRRITANT
HS Code 
29339900
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Ethyl 2-aminothiazole-5-carboxylate Usage And Synthesis

Chemical Properties

White to yellow or light brown crystal or powder

Uses

2-Amino-5-thiazolecarboxylic Acid Ethyl Ester is used in the synthesis of dual-action antidiabetic agents that inhibit glycogen phosphorylase.

Synthesis Reference(s)

Tetrahedron Letters, 42, p. 2101, 2001 DOI: 10.1016/S0040-4039(01)00161-7

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