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3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline

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3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Basic information

Product Name:
3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
Synonyms:
  • 3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline
  • Benzenamine, 3-(1H-imidazol-1-yl)-5-(trifluoromethyl)-
CAS:
943320-48-7
MF:
C10H8F3N3
MW:
227.19
Mol File:
943320-48-7.mol
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3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Chemical Properties

Boiling point:
365.8±42.0 °C(Predicted)
Density 
1.39±0.1 g/cm3(Predicted)
pka
5.31±0.10(Predicted)
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3-(1H-imidazol-1-yl)-5-(trifluoromethyl)aniline Usage And Synthesis

Uses

3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline is a reactant used in the synthesis of novel Bcr/Abl inhibitors as anti-cancer drugs. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia.

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