Basic information Safety Supplier Related

PLX8394

Basic information Safety Supplier Related

PLX8394 Basic information

Product Name:
PLX8394
Synonyms:
  • PLX8394
  • PLX8394;PLX-8394;PLX 8394
  • 1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-
  • (R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide
  • (3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide
  • PLX8394,PLX-8394
  • plixorafenib
  • (R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
CAS:
1393466-87-9
MF:
C25H21F3N6O3S
MW:
542.53
Mol File:
1393466-87-9.mol
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PLX8394 Chemical Properties

Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 39 mg/mL (71.89 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
6.33±0.40(Predicted)
color 
White to light yellow
InChIKey
YYACLQUDUDXAPA-MRXNPFEDSA-N
SMILES
N1(S(NC2=CC=C(F)C(C(C3C4=CC(C5=CN=C(C6CC6)N=C5)=CN=C4NC=3)=O)=C2F)(=O)=O)CC[C@@H](F)C1
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Safety Information

HS Code 
2935909099
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PLX8394 Usage And Synthesis

Uses

Combination therapies comprising KRAS G12C inhibitors and Raf kinase inhibitors for treating KRAS G12C cancers.BRAF inhibitor.

PLX8394Supplier

ShangHai ChuanQian Chemcial Technique Centre Gold
Tel
15869524721
Email
3525679403@qq.com
Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd. Gold
Tel
17752881701
Email
190060276@qq.com
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 17702719238
Email
sales@sun-shinechem.com
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Email
info@chemexpress.com
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PLX8394(1393466-87-9)Related Product Information