DBCO-PEG5-NHS ester Chemical Properties

Density 

1.32±0.1 g/cm3(Predicted)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

Acetonitrile (Slightly), Chloroform (Slightly)

form 

Oil

pka

15.14±0.46(Predicted)

color 

Yellow to Dark Yellow

DBCO-PEG5-NHS ester Usage And Synthesis

Description

DBCO-NHCO-PEG5-NHS ester is a PEG linker containing NHS ester that is able to react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG spacer arm improves water solubility and can also provide a long and flexible connection that minimizes steric hindrance during ligation. DBCO is commonly used for copper-free Click Chemistry reactions.

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