Basic information Safety Supplier Related

Lotusine

Basic information Safety Supplier Related

Lotusine Basic information

Product Name:
Lotusine
Synonyms:
  • Lotusine
  • (1R)-1,2,3,4-Tetrahydro-6-hydroxy-1-[(4-hydroxyphenyl)methyl]-7-methoxy-2,2-dimethylisoquinolinium
  • D-(-)-Lotusine
  • (-)-Lotusine
  • inhibit,Lotusine,Inhibitor
  • (R)-6-Hydroxy-1-(4-hydroxybenzyl)-7-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolin-2-ium
  • lidenine
  • Lotusine, 10 mM in DMSO
CAS:
6871-67-6
MF:
C19H24NO3+
MW:
314.4
Mol File:
6871-67-6.mol
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Lotusine Chemical Properties

solubility 
DMF: 5 mg/ml; DMSO: 10 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 5 mg/ml
form 
A solid
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Lotusine Usage And Synthesis

Description

A quaternary benzylisoquinoline alkaloid found in the seeds of Neiumbo nuci· [era, the base occurs in the non-phenolic fraction of the alkaloidal extract. Two phenolic hydroxyl groups and a methoxyl group are present.

Chemical Properties

White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from lotus seeds Nelumbo nucifera.

Uses

Lotusine is a pure alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn. Lotusine shows effects on the action potentials in myocardium and slow inward current in cardiac Purkinje fibers[1].

Definition

ChEBI: Lotusine is a member of isoquinolines.

References

Yang, Chen., J. Chin. Chem. Soc., 17, 235 (1970)

LotusineSupplier

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