SU5208 Chemical Properties

Boiling point:

448.0±45.0 °C(Predicted)

Density 

1.350±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

solubility 

DMSO: 45 mg/mL (197.99 mM);Ethanol: 2 mg/mL (8.80 mM)

pka

11.90±0.20(Predicted)

form 

Solid

color 

Yellow to orange

Water Solubility 

Water: Insoluble

SU5208 Usage And Synthesis

Uses

SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2)[1].

IC 50

VEGFR2

References

[1] Camila Mu?oz, et al. Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations. J Mol Graph Model. 2012 Feb;32:39-48. DOI:10.1016/j.jmgm.2011.10.005

SU5208(62540-08-3)Related Product Information

• SU 5416
• SU4312
• SU 9516
• su5204
• SU 5214
• 5-CHLORO-3-[(3,5-DIMETHYLPYRROL-2-YL)METHYLENE]-2-INDOLINONE
• VEGFR2 Kinase Inhibitor I
• IC 261
• SU 5205
• NSC 247030