su5204
su5204 Basic information
- Product Name:
- su5204
- Synonyms:
-
- 2H-Indol-2-one, 3-[(2-ethoxyphenyl)methylene]-1,3-dihydro-
- 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one
- HER1,Vascular endothelial growth factor receptor,SU 5204,inhibit,SU5204,VEGFR,ErbB-1,Epidermal growth factor receptor,EGFR,SU-5204,Inhibitor
- SU5204, 10 mM in DMSO
- SU5204 ，S0290
- CAS:
- 186611-11-0
- MF:
- C17H15NO2
- MW:
- 265.31
- Mol File:
- 186611-11-0.mol
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su5204 Chemical Properties
- Boiling point:
- 476.9±45.0 °C(Predicted)
- Density
- 1.209±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 100 mg/mL (376.92 mM)
- pka
- 12.82±0.20(Predicted)
- form
- Solid
- color
- Light yellow to yellow
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su5204 Usage And Synthesis
Uses
SU5204, a tyrosine kinase inhibitor, has IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively[1].
IC 50
VEGFR2: 4 μM (IC50); HER2: 51.5 μM (IC50)
References
[1] Peng Cho Tang, et al. 3-heteroaryl-2-indolinone compounds for the treatment of disease. US5792783A.
su5204Supplier
Shanghai Lollane Biological Technology Co.,Ltd.
- Tel
- 021-52996696，15000506266 15000506266
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
ShangHai Biochempartner Co.,Ltd
- Tel
- 177-54423994 17754423994
- 2853530910@QQ.com
Twochem Co.Ltd.
- Tel
- 021-58111628 15800915896
- sales@twochem.com